Source Themes

Are Mendelian randomization investigations immune from bias due to reverse causation?

Reverse causation can also cause problems for Mendelian randomization.

Do Case-Control Studies Always Estimate Odds Ratios?

A short manuscript demonstrating that estimates from most case-control designs cannot be interpreted as odds ratios.

Mendelian randomization with multiple exposures-the importance of thinking about time

How do mediation models work with time-varying variables in Mendelian randomization studies.

From GWAS to PheWAS: the search for causality in big data

Causal discovery using GWAs and PheWAS.

Interpretation and Potential Biases of Mendelian Randomization Estimates With Time-Varying Exposures

A precise defintion of the type of lifetime effect that is estimated by Mendelian randomization and when it isn't possible to estimate this effect.

Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

How to think about and perform Mendelian randomization analyses with binary exposures.

Understanding the Assumptions Underlying Instrumental Variable Analyses: a Brief Review of Falsification Strategies and Related Tools

Falsification tests and sensitivity analyses for IV methods.